VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
-
CH5183284 是一种选择性口服有效的FGFR抑制剂，对FGFR1，FGFR2，FGFR3，和 FGFR4的IC50分别为 9.3 nM，7.6 nM，22 nM，和 290 nM 。Phase 1。
More
-
Bindarit 选择性抑制炎症趋化因子亚家族，包括单核细胞趋化蛋白 MCP-1/CCL2， MCP-3/CCL7和MCP-2/CCL8。
More
-
Irsogladine是一种抗胃溃疡剂，通过M1 muscarininc乙酰胆碱受体结合，有利于细胞间隙连接通讯。
More
-
Silibinin为抗癌和化疗预防化合物，能抑制细胞增殖和迁移。
More
-
URMC-099是MLK3口服活性，脑渗透性抑制剂，IC50值14nM，抑制脂多糖诱导的小胶质细胞TNF的释放。
More
