VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Tanshinone IIA是丹参和Salviae miltiorrhizae Radix中最丰富的二萜醌类，用于治疗心血管疾病和炎症性疾病。
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Carbidopa (卡比多巴) 是多巴脱羧酶抑制剂，可作用于帕金森症。
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Eplerenone是醛固酮拮抗剂，IC50为360nM。
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CH5183284 是一种选择性口服有效的FGFR抑制剂，对FGFR1，FGFR2，FGFR3，和 FGFR4的IC50分别为 9.3 nM，7.6 nM，22 nM，和 290 nM 。Phase 1。
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Bindarit 选择性抑制炎症趋化因子亚家族，包括单核细胞趋化蛋白 MCP-1/CCL2， MCP-3/CCL7和MCP-2/CCL8。
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