VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
-
OTSSP167是一种高效的MELK(母体胚胎亮氨酸拉链激酶)抑制剂,IC50为0.41 nM。
More
-
Nitazoxanide是抗原生动物化合物,对犬流感病毒的IC50为0.17 到 0.21μM。
More
-
Hyodeoxycholic (HDCA) acid 是一种次要的胆汁酸,是肠道细菌的代谢产物之一。
More
-
Tigecycline 是首创的广谱抗生素,对多种抗生素抗性菌同样有效。
More
-
4EGI-1是通过结合eIF4E,竞争性的作用于eIF4E/eIF4G相互作用的抑制剂, 其KD值为25 μM。
More