VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Indapamide可作用于钾离子通道,是非噻嗪类磺胺类利尿剂。
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Sevelamer hydrochloride是结合磷酸盐化合物,可用于高磷血症。
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XEN445 是一种有效的选择性 endothelial lipase 抑制剂,IC50为0.237 μM。
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