VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Eltrombopag是口服活性的促血小板生成素受体激动剂。
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Neomycin sulfate是氨基糖苷类抗生素,是钙离子通道抑制剂。
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HC-030031是TRPA1通道阻断剂,能拮抗AITC和福尔马林诱发的钙流,IC50分别为6.2 μM和5.3 μM。
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Liothyronine Sodium是甲状腺激素的最有效形式,提高基础代谢率,影响蛋白质的合成。
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CORM-3 是水溶性一氧化碳的释放分子,具有抗炎和保护心脏的作用。
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