VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Rimantadine是抗流感病毒化合物。
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Tiotropium Bromide hydrate是长效的毒蕈碱受体拮抗剂。
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Sodium Picosulfate能抑制水和电解质的吸收,增加它们的分泌。
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Daidzein是genistein的钝化类似物,是酪氨酸激酶抑制剂和雌激素受体活化剂。
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AZD7545是PDHK抑制剂,对PDHK1和PDHK2的IC50分别为36.8 nM和6.4 nM。
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