VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
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    Ro3280是一种有效的,高选择性Polo-like kinase 1(PLK1)抑制剂,IC50为3 nM。

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  • Scopolamine HBr EY0879

    Scopolamine hydrobromide (氢溴酸东莨菪碱) 是毒蕈碱乙酰胆碱受体(mAChR)拮抗剂,IC50为55.3 nM。

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    Oseltamivir phosphate磷酸盐是神经氨酸酶抑制剂,具有抗流感病毒活性。

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    Thiamphenicol为抗菌素,是氯霉素的甲磺酰类似物。

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  • MI-2 EY0843

    MI 2是MALT1的不可逆抑制剂,在ABCDLBCL细胞增殖抑制实验中IC50为5.84 uM。

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