VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Quercetin Dihydrate是一种广泛分布于植物的黄酮类,是一种抗氧化剂,与许多其他酚类杂环化合物类似。
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Bisacodyl是一种刺激性泻药,直接作用于结肠产生排便效应。
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Clindamycin通过作用于50S ribosomal subunits(50S核糖体亚基)而抑制蛋白合成。
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Sal003是eIF2α phosphatase高效细胞渗透性抑制剂,Salubrinal的水溶性类似物。
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Doxapram hydrochloride hydrate (盐酸多沙普仑水合物) 能抑制TASK-1,TASK-3和TASK-1/TASK-3异二聚体通道,EC50分别为410 nM,37 μM和9 μM。
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