VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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NAD+即烟酰胺腺嘌呤二核苷酸,是一种转递氢离子的辅酶。
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Kaempferol天然无毒可降低卵巢癌患病风险。
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Fosaprepitant dimeglumine 是神经激肽-1受体拮抗剂,可作用于化疗引起的恶心呕吐。
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Chlorzoxazone是一种作用于中枢的肌肉松弛剂, 用于治疗肌肉痉挛,作为人体肝脏细胞色素P-450IIE1的探针。
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CCG 50014是一种强有效和选择性的抑制剂,靶点为G蛋白信号转导蛋白调节器(RGS),对RGS4的IC50为30 nM,比其它RGS蛋白选择性高20倍。
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