VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Chlorzoxazone是一种作用于中枢的肌肉松弛剂, 用于治疗肌肉痉挛,作为人体肝脏细胞色素P-450IIE1的探针。
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CCG 50014是一种强有效和选择性的抑制剂,靶点为G蛋白信号转导蛋白调节器(RGS),对RGS4的IC50为30 nM,比其它RGS蛋白选择性高20倍。
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Arecoline hydrobromide是毒蕈碱乙酰胆碱受体(mAChR)激动剂。
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Oxybutynin 是一种抗胆碱药,用于减少尿量,减轻膀胱负担。
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L-Thyroxine能降低总胆固醇水平,低密度脂蛋白。
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