VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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黄芪甲苷Astragaloside A(Astragaloside IV)是黄芪在中医的主要活性成分;已广泛用于治疗缺血性疾病。
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Formononetin (Formononetol; Flavosil)提取自红三叶草,能剂量依赖的抑制DU-145/PC-3细胞增殖。
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Amphotericin B是抗真菌类抗生素,由结节链霉菌中的一种菌株产生,IC50为0.028到0.290 μg/ml。
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PTC-209氢溴酸盐是特异的BMI-1抑制剂,IC50为0.5 uM。
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Tioconazole是抗真菌剂。
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