VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Lonidamine是口服活性的己糖激酶抑制剂。
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Cyromazine 是三聚氰胺的环丙基衍生物,是一种昆虫生长调节剂,用作杀虫剂和杀螨剂,通过影响某些昆虫幼虫阶段的神经系统而起作用。
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TAPI-1 is an ADAM17/TACE inhibitor that blocks shedding of cytokine receptors with IC50 value of 8.09 microM.
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Chlorpropamide是一种口服降糖剂, 用于治疗非胰岛素依赖型糖尿病 (NIDDM)。
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Oridonin是从Rabdosia rubescens中分离的对映贝壳杉烷二萜,是一种重要的传统中药。
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