VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Kinetin是一种参与细胞分裂的植物生长激素。
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GW2580是c-FMS激酶口服活性抑制剂,体外实验60nM浓度能完全抑制c-FMS酶活性,对其他26种激酶没有抑制作用。
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RI-1是RAD51抑制剂,IC50在5到30 μM之间。
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Phlorizin是天然产物,是经典的hSGLT1和hSGLT2的抑制剂,Ki分别为300 nM和39 nM。
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4-Methylumbelliferone (4-MU)是透明质酸(HA)合成抑制剂,IC50为0.4 mM。
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