VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Artesunate 是一种抗疟类药,作用于小细胞肺癌细胞系H69,IC50为< 5 μM。
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FPH2 (BRD-9424) 是一种小分子,可促进iPS衍生肝细胞的分化。
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Volasertib(BI6727)是高活性PLK1抑制剂,IC50为0.87 nM,比对Plk2和Plk3的抑制性高6倍和65倍。
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Droperidol是一种丁酰苯类的Dopamine-2受体拮抗剂。
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Atropine sulfate monohydrate是毒蕈碱乙酰胆碱受体拮抗剂。
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