VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
-
Solifenacin Succinate (琥珀酸索利那新; YM905; Vesicare) 是毒蕈碱受体拮抗剂。
More
-
Lomitapide(AEGR-733, BMS-201038)是一种高效MTP蛋白抑制剂,体外IC50值为8nM。
More
-
Closantel是一种革兰氏阳性的抗菌活性抑制剂,抑制KinA/Spo0F系统,IC50为3.8 μM。
More
-
Quinacrine是一种荧光探针,使胆碱能受体蛋白发生构象转变,低μM水平对AML细胞具有作用活性,平均IC50为2.30 μM。
More
-
JZL 184是MAGL的有效选择性抑制剂,IC50值为8nM,对FAAH的IC50值为4uM。
More