VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Sesamin 是从Fagara植物的树皮和芝麻油中分离的一种木脂素。
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Rhein 是一种蒽醌类化合物,具有抗炎、抗氧化、抗癌等作用。
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Solifenacin Succinate (琥珀酸索利那新; YM905; Vesicare) 是毒蕈碱受体拮抗剂。
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Lomitapide(AEGR-733, BMS-201038)是一种高效MTP蛋白抑制剂,体外IC50值为8nM。
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Closantel是一种革兰氏阳性的抗菌活性抑制剂,抑制KinA/Spo0F系统,IC50为3.8 μM。
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