VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Darifenacin hydrobromide (氢溴酸达非那新; UK88525) 是选择性M3蕈毒碱受体拮抗剂,pKi为8.9。
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Protionamide可作用于结核病和麻风病。
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Ethambutol双盐酸盐是抗分枝杆菌化合物,能通过抑制阿拉伯糖基转移酶活性阻止细胞壁的形成。
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Aloe emodin是从芦荟叶中提取出的羟基蒽醌,已被证明体外和体内抗肿瘤活性。
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Pranoprofen是非甾体抗炎化合物,可作用于眼科疾病。
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