Home > Signal Pathway > Transmembrane Transporters > VDAC

VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

  • Mitotane EY1695

    Mitotane是DDD的同分异构体和DDT的衍生物，有抗癌活性，可作用于肾上腺皮质癌。

    More

  • Methscopolamine EY1696

    Methscopolamine是一种毒蕈碱型乙酰胆碱受体抑制剂。

    More

  • Flufenamic acid EY1685

    Flufenamic acid是非甾体类抗炎药物, 是一种环氧合酶抑制剂，且抑制前列腺素的形成, 结合且降低前列腺素合成酶的活性, 及激活TRPC6。

    More

  • CID755673 EY1666

    CID755673是细胞活性的PKD抑制剂，IC50为182 nM，与AKT，PLK1，CAK，CAMKIIα及PKC各亚型相比，可选择性抑制PKD1。

    More

  • Febuxostat EY1669

    Febuxostat是选择性黄嘌呤氧化酶（XO）抑制剂，Ki为0.6 nM。

    More
    • Current page208, Total Pages252, Total Record1257 First Prev 206207208209210 Next Last Goto
More