VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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PTC-209是特异的BMI-1抑制剂，IC50为0.5 uM。并能不可逆的减少癌起始细胞(CICs).
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UM171是一种有效的人造血干细胞再生激动剂，激动作用不被 AhR 的抑制影响。
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Roxithromycin 是一种半合成的大环内酯类抗生素，用于治疗呼吸道，泌尿及软组织感染。
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BTZ043是DprE1的抑制剂，它在结核杆菌中有低浓度的抗菌活性。
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Neohesperidin dihydrochalcone(Nhdc), sometimes abbreviated to neohesperidin DC or simply NHDC, is an artificial sweetener derived from citrus.
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