Cariporide (HOE-642), a potent NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1). IC50: 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2, respectively.
MoreLPS (Lipopolysaccharide) is an endotoxin which exists as a critical glycolipid component of the outer cell wall of gram-negative bacteria. It induces apoptosis in mouse thymus and swine lymphocytes and also an activator of TLR4 and TNF receptor signaling pathways.
MoreSelective toll-like receptor 1/2 (TLR1/2) inhibitor。
MoreSodium oxamate inhibits lactate dehydrogenase(LDH)and is an inhibitor of gluconeogenesis and glycolysis.
MoreCefoperazone (头孢哌酮) 是头孢菌素类抗生素。
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