ATN-224为铜螯合剂,抑制细胞内的SOD1活性(IC50为17.5 nM)。
MoreResatorvid是TLR4信号通路抑制剂,能通过结合TLR4胞内区域抑制脂多糖诱导的炎症介质的产生。
MoreCariporide (HOE-642), a potent NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1). IC50: 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2, respectively.
MoreLPS (Lipopolysaccharide) is an endotoxin which exists as a critical glycolipid component of the outer cell wall of gram-negative bacteria. It induces apoptosis in mouse thymus and swine lymphocytes and also an activator of TLR4 and TNF receptor signaling pathways.
MoreSelective toll-like receptor 1/2 (TLR1/2) inhibitor。
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