VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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AZD3759是一种有效的EGFR抑制剂, 抑制EGFR TK野生型, L858R 突变型, 和 Exon 19Del 酶的IC50值分别为0.3, 0.2, 和 0.2 nM。
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ML 224 是促甲状腺激素受体TSHR反激动剂，IC50值为2.3uM。
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KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes.
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Atractylenolide-I是从白术中提取的一种天然化合物，可诱导细胞凋亡而导致HL-60细胞的细胞毒性，TLR4拮抗剂。
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Nile red是脂质定位和定量（主要是在含有中性脂质液滴的细胞）。
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