VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
-
AZD4547是一种新型选择性的FGFR抑制剂,靶向作用于FGFR1/2/3,IC50为0.2 nM/2.5 nM/1.8 nM,对FGFR4, VEGFR2(KDR)具有微弱的作用活性,但对IGFR, CDK2和p38几乎没有作用活性。
More
-
Coenzyme Q10 (CoQ10) 组成电子传递链,并参与细胞有氧呼吸.
More
-
AZ191是DYRK1B高效选择性抑制剂,IC50值17nM。
More
-
Tempol是一种超氧化物清除剂,具有神经保护,抗炎症和镇痛效果。
More
-
Acarbose是α-葡糖苷酶抑制剂,有抗2型糖尿病功效。
More