VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
  • IPSU EI1359

    IPSU是OX2 受体拮抗剂, 口服有效。

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  • INCA-6 EI1346

    INCA-6是Calcineurin-substrate association抑制剂。

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  • INCB 3284 dimesylate EI1347

    INCB 3284 dimesylate是选择性 CCR2 拮抗剂。

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  • Indibulin EI1349

    Indibulin是Microtubule destabilizer。

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  • INDY EI1350

    INDY是DYRK1A/B 抑制剂。

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