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VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

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    ML 382是MrgX1 (SNSR4) 阳性变构的调节剂（positive allosteric modulator）。

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  • ML 7 hydrochloride EI1729

    ML 7 hydrochloride是肌球蛋白轻链(Myosin light chain)激酶选择性抑制剂。

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  • ML 221 EI1714

    ML 221是Apelin 受体 (APJ) 拮抗剂。

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  • ML 281 EI1717

    ML 281是STK33 抑制剂。

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  • ML 154 EI1704

    ML 154是活性的neuropeptide S receptor (NPSR) 拮抗剂。

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