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VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

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    ML 154是活性的neuropeptide S receptor (NPSR) 拮抗剂。

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  • ML 171 EI1706

    ML 171是选择性 NADPH oxidase 1 (NOX1) 抑制剂。

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  • ML 202 EI1711

    ML 202是Pyruvate kinase M2 激动剂。

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    MK 217是Farnesyl diphosphate synthase的抑制剂(FPPS)，破骨细胞介导的骨吸收抑制剂（osteoclast-mediated bone resorption）。

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