VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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N1,N12-Diethylspermine tetrahydrochloride是Polyamine synthase 的抑制剂。
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N2-Methyl-L-arginine是Lysosomal system c L-arginine uptake inhibitor(摄取抑制剂)。
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N-Acetylcysteine amide是Glutathione (GSH) 前体, 具有神经保护性。
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N,N-Dimethylsphingosine是Sphingosine 激酶抑制剂。
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MSC 2032964A是活性的,选择性 ASK1 抑制剂, 口服有效。
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