VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Olmesartan是活性的 AT1 拮抗剂, Olmesartan medoxomil的代谢产物。
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Olmesartan medoxomil是选择性非肽类 AT1 拮抗剂, Olmesartan的前药。
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Octopamine hydrochloride是无脊椎生物胺 可以激活 β3 肾上腺素能受体(invertebrate biogenic amine,activates β3 adrenoceptors)。
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ODQ
EI1992
ODQ是NO-sensitive guanylyl cyclase选择性抑制剂。
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OGT 2115是抗血管新生活性。 Heparanase的抑制剂。
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