VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Pemoline是Pemoline is CNS stimulant and an indirect monoamine activator。
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PD 158780是活性的 ErbB 受体家族抑制剂。
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PD 160170是选择性非肽类 NPY Y1 受体拮抗剂。
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PD 161570是选择性 FGFR 抑制剂。
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PD 166285 dihydrochloride是活性的 Src 抑制剂, 也能抑制 FGFR1, PDGFRβ 和 Wee1。
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