VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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PF 543 hydrochloride是活性的,选择性 SphK1 抑制剂。
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PF 8380是活性的 autotaxin 抑制剂。
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PF 184是活性的,选择性 IKKβ 抑制剂。
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PF 3644022是活性的 MK2 抑制剂。
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PF 429242是SREBP site 1 蛋白酶竞争性抑制剂。
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