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VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

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    PG-9 maleate是突触前胆碱能调节剂(Presynaptic cholinergic modulator)。

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  • PF 5081090 EI2131

    PF 5081090是活性的 LpxC 抑制剂。

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  • PF 543 hydrochloride EI2134

    PF 543 hydrochloride是活性的，选择性 SphK1 抑制剂。

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  • PF 8380 EI2137

    PF 8380是活性的 autotaxin 抑制剂。

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  • PF 184 EI2124

    PF 184是活性的，选择性 IKKβ 抑制剂。

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