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VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

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    PF9 tetrasodium salt是活性的 GPR17 激动剂。

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    PFI 4是活性的，选择性 BRPF1 bromodomain 抑制剂。

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