VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
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    PMX 464是PMX 464 is a putative inhibitor of the Trx-TrxR system具有抗肿瘤增殖活性。。

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  • PK 11195 EI2182

    PK 11195是Peripheral benzodiazepine受体的拮抗剂。

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  • Plumbagin EI2193

    Plumbagin是诱导G2/M细胞周期捕获,具有抗肿瘤活性。。

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  • PLX 647 dihydrochloride EI2194

    PLX 647 dihydrochloride是活性的双效 Fms/KIT 抑制剂。

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  • PMPA (NAALADase inhibitor) EI2196

    PMPA (NAALADase inhibitor)是GCP II 抑制剂。

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