VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 
  • Pyrintegrin EI2277

    Pyrintegrin是增强人胚胎干细胞酶解之后的存活(ESCs after enzymatic dissociation)。

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  • PTAC oxalate EI2270

    PTAC oxalate是Muscarinic 受体配体,在其不同的亚型上会展现部分激动或者拮抗的活性。

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  • PRT 4165 EI2248

    PRT 4165是Bmi1/Ring1A的抑制剂,可以抑制组蛋白H2A泛素化(ubiquitination)。

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  • PS 1145 dihydrochloride EI2249

    PS 1145 dihydrochloride是选择性 IKK 抑制剂, 口服有效。

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  • PSB 06126 EI2252

    PSB 06126是NTPDase 3 抑制剂。

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