VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Ro 5-3335是Core binding factor的抑制剂可以削弱造血功能（hematopoiesis）。
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Ro 61-8048是活性的 kynurenine 3-monooxygenase (KMO) 抑制剂。
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Ro 19-4603是Benzodiazepine 反向激动剂。
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Ro 26-4550 trifluoroacetate是Ro 26-4550 trifluoroacetate是IL-2和IL-2Rα 受体相互作用的竞争性抑制剂。
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Ro 48-8071 fumarate是2，3-Oxidosqualene cyclase (OSC) 抑制剂，可以阻止胆固醇的合成（cholesterol synthesis）。
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