VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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SB 657510是选择性 urotensin-II (UT) 受体拮抗剂。
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SB 706375是高亲和性,非肽类 UT 受体拮抗剂。
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SC 144 hydrochloride是gp130抑制剂(SC 144 hydrochloride blocks cytokine-triggered gp130 signaling)。
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SB 611812是Urotensin-II (UT) 拮抗剂可以减弱心功能不全的问题。。
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SB 612111 hydrochloride是选择性NOP受体拮抗剂。
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