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VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

  • UNC 2327 EI2867

    UNC 2327是PRMT3变构的抑制剂（allosteric modulator）。

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  • UNC 2400 EI2868

    UNC 2400是Negative control of UNC 1999 。

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  • UNC 3230 EI2869

    UNC 3230是活性的，选择性 PIP5K1C 抑制剂， antinociceptive activity。

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  • UNC 926 hydrochloride EI2870

    UNC 926 hydrochloride是L3MBTL1 domain 抑制剂。

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  • UPF 648 EI2871

    UPF 648是活性kynurenine 3-monooxygenase (KMO) 抑制剂。

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