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VDAC


VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane. 

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    VU 0469650 hydrochloride是活性的，选择性mGlu1阴性变构的调节剂（negative allosteric modulator）。

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  • VU 0255035 EI2898

    VU 0255035是高选择性muscarinic M1受体的拮抗剂。

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  • VU 0357017 hydrochloride EI2900

    VU 0357017 hydrochloride是M1受体阳性变构的调节剂（positive allosteric modulator）。

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  • VTP 27999 trifluoroacetate EI2892

    VTP 27999 trifluoroacetate是高活性选择性肾素(renin)抑制剂。

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  • VU 0155069 EI2895

    VU 0155069是活性的，选择性 PLD1 抑制剂。

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