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TRP Channel


TRP channels (Transient receptor potential channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. There are about 28 TRP channels that share some structural similarity to each other. These are grouped into two broad groups: Group 1 includes TRPC,TRPV,TRPM,TRPN, and TRPA. In group 2, there are TRPP ,and TRPML. Many of these channels mediate a variety of sensations like the sensations of pain, hotness, warmth or coldness, different kinds of tastes, pressure, and vision. TRPs have been seen to have complex multidimensional roles in sensory signaling. Many TRPs function as intracellular calcium release channels.

  • WS 3 EI2949

    WS 3是TRPM8激动剂并且是个冷却剂。

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  • TCS 5861528 EI2734

    TCS 5861528是TRPA1 阻断剂。

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  • TC-I 2000 EI2711

    TC-I 2000是TRPM8通道的阻断剂。

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  • TC-I 2014 EI2712

    TC-I 2014是活性的TRPM8拮抗剂。

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  • STEARDA EI2636

    STEARDA是内源性脂类，在体内生物有效。STEARDA enhances effects of endovanilloids at TRPV1 receptors.。

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