Cellular microbiology attempts to use pathogenic microbes as tools for cell-biology research, and to employ cell-biology methods to understand the pathogenicity of microbes. Toxins and virulence factors from microbes have been used for decades to influence processes in eukaryotic cells and to study them. It has increasingly appeared that applying a purified toxin on a cell does not always provide the complete picture, and that understanding the role of the toxin in pathogenicity, the way the toxin promotes the microbe, the way the toxin is produced and the co-evolution of the toxin and its host-cell counterparts, is crucial.
PQ 69是活性选择性 A1 拮抗剂/反向激动剂。
MorePNU 74654是能和β-catenin相互结合, 抑制 Wnt 信号通路。
MorePD 81723是A1 受体的变构增强剂(allosteric potentiator)。
MoreN6-Cyclopentyladenosine是活性的, 选择性 A1 激动剂。
MoreMRS 3777 hemioxalate是高亲和性 选择性 A3 拮抗剂。
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