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Metabolism


Metabolism is the set of life-sustaining chemical transformations within the cells of living organisms. The three main purposes of metabolism are the conversion of food/fuel to energy to run cellular processes, the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates, and the elimination of nitrogenous wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. 

  • SB742457 EY1131

    SB742457是5-HT6受体拮抗剂，pKi为9.63，比对其它受体的抑制性高100倍以上。

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  • VX-745 EY1096

    VX-745是一种有效的，选择性p38α抑制剂，IC50为10 nM，比作用于p38β选择性高22倍，对p38γ没有抑制作用。

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  • SD-208 EY0968

    SD-208是口服活性的ATP竞争性TGF-βRI抑制剂，IC50为49 nM，比对TGF-βRII和其它激酶的抑制性高100倍和17倍。

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  • SB269970 HCl EY0909

    SB269970盐酸盐是5-HT7受体拮抗剂，pKi为8.3，比对其它受体的抑制性高50倍以上。

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  • Risperidone EY0910

    Risperidone（R64766）是5-HT2受体阻断剂和多巴胺D2受体拮抗剂，Ki值分别为0.16和1.4nM。

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