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Metabolism


Metabolism is the set of life-sustaining chemical transformations within the cells of living organisms. The three main purposes of metabolism are the conversion of food/fuel to energy to run cellular processes, the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates, and the elimination of nitrogenous wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. 

  • TAK-715 EY1557

    TAK-715是一种p38 MAPK抑制剂，作用于p38α，IC50为7.1 nM，作用于p38α比作用于p38β选择性高28倍多，对p38γ/δ， JNK1， ERK1， IKKβ， MEKK1和TAK1没有抑制作用。

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  • Urapidil HCl EY1565

    Urapidil HCl是Urapidil的盐酸盐形式，是α1-肾上腺素能受体拮抗剂和5-HT1A受体激动剂，pIC50分别为6.13和6.4。

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  • Escitalopram Oxalate EY1510

    Escitalopram oxalate是选择性5羟色胺重吸收抑制剂（SSRI），Ki为0.89 nM。

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  • Sumatriptan Succinate EY1445

    Sumatriptan succinate是5-HT1受体激动剂，可作用于偏头疼。

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  • Ziprasidone HCl EY1449

    Ziprasidone盐酸盐是5-HT和多巴胺受体拮抗剂，有抗精神病活性。

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