Cyclophosphamide is a nitrogen mustard alkylating agent. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring.
MoreMLN4924是一种有效的选择性NEDD8活化酶(NEDD8-activating enzyme,NAE)抑制剂,IC50为4.7 nM。
MoreCREB 666-15是有效选择性的CREB抑制剂,IC50值为81 nM。
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