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Other Singal pathway


  • Splitomicin EY0490

    Splitomicin是一种选择性的NAD(+)-dependent histone deacetylase Sir2p抑制剂，IC50为60 μM。在细胞中有着更高的活性。

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  • SNS-032 EY0491

    SNS-032是CDK 9，2和7的抑制剂，IC50分别为4，38和62 nM。

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  • Pelitinib EY0470

    Pelitinib (EKB-569; WAY-EKB 569)是不可逆的EGFR抑制剂，IC50为38.5 nM。

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  • Miglitol EY0477

    Miglitol是口服的抗糖尿病化合物，能抑制糖复合体分解为葡萄糖。

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  • PF-431396 EY0478

    PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively), PF-431396 has a Kd value of 445 nM for BRD4.

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