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Other Singal pathway


  • CP-640186 hydrochloride EY2036

    CP-640186 hydrochloride是乙酰辅酶A羧化酶（ACCase）抑制剂，对鼠肝ACCase1和骨骼肌ACCase2的IC50s分别为53 nM和61 nM。

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  • AP26113 EY2037

    AP26113是一种有效的ALK抑制剂，无细胞试验中IC50为0.62 nM，能够克服L1196M突变介导的Crizotinib耐药性。

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  • AZD3759 EY2038

    AZD3759是一种有效的EGFR抑制剂, 抑制EGFR TK野生型, L858R 突变型, 和 Exon 19Del 酶的IC50值分别为0.3, 0.2, 和 0.2 nM。

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  • ML 224 EY2039

    ML 224 是促甲状腺激素受体TSHR反激动剂，IC50值为2.3uM。

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  • NSC 636819 EY2027

    KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes.

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