FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
MoreVO-OHpic trihydrate是PTEN(phosphatase and tensin homologue deleted on chromosome 10)高活性抑制剂,IC50值为35 nM。
MoreFirategrast是口服有效的整合素α4β1/α4β7小分子拮抗剂。
MoreFAK Inhibitor 14 is a selective focal adhesion kinase (FAK) inhibitor, it prevents FAK autophosphorylation at Y397 (IC50 = 1μM).
MoreMyD88的二聚化抑制剂。
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