SF1670是一种有效的PTEN特异性抑制剂,同时对CD45具有高效抑制活性,最好的IC50数值为200 nM。
MoreL-755,507 enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). L-755,507 is also a very potent and selective β3-AR adrenergic receptor partial agonist, selective over both β1-AR and β2-AR adrenoceptor binding.
MoreATN-224为铜螯合剂,抑制细胞内的SOD1活性(IC50为17.5 nM)。
MoreResatorvid是TLR4信号通路抑制剂,能通过结合TLR4胞内区域抑制脂多糖诱导的炎症介质的产生。
MoreCariporide (HOE-642), a potent NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1). IC50: 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2, respectively.
More