Guggulsterone can act as an antagonist ligand for farnesoid X receptor (FXR) and decrease expression of bile acid-activated genes.
MorePotent inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases. Causes ER stress; can be used to induce autophagy in mammalian cells.
MoreSF1670是一种有效的PTEN特异性抑制剂,同时对CD45具有高效抑制活性,最好的IC50数值为200 nM。
MoreL-755,507 enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). L-755,507 is also a very potent and selective β3-AR adrenergic receptor partial agonist, selective over both β1-AR and β2-AR adrenoceptor binding.
MoreATN-224为铜螯合剂,抑制细胞内的SOD1活性(IC50为17.5 nM)。
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