Nile red是脂质定位和定量(主要是在含有中性脂质液滴的细胞)。
MoreML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B, and minimal activity against a panel of other kinases tested.
MoreInhibits calcium-sensitive chloride currents (10 μM). Putative GPR35 agonist.
More2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic Acid Ethyl Ester is a boronic acid ester derivative that inhibits HSL (hormone-sensitive lipase)
MoreSR 11302 is an inhibitor of activator protein-1 (AP-1), a transcription factor that displays antitumor activity. SR 11302 does not activate transcription from the retinoic acid response element (RARE) and also does not display activity at retinoic acid receptors (EC50 > 1 μM for RARα, RARβ, and RARγ).
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