ML 224 是促甲状腺激素受体TSHR反激动剂,IC50值为2.3uM。
MoreKDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes.
MoreAtractylenolide-I是从白术中提取的一种天然化合物,可诱导细胞凋亡而导致HL-60细胞的细胞毒性,TLR4拮抗剂。
MoreNile red是脂质定位和定量(主要是在含有中性脂质液滴的细胞)。
MoreML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B, and minimal activity against a panel of other kinases tested.
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