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Other Singal pathway


  • Filgotinib EY0740

    Filgotinib (GLPG0634) is the first selective inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively.

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  • AZD1480 EY0751

    AZD1480是一种新型，ATP竞争性的JAK2抑制剂，IC50为0.26 nM，选择性作用于JAK3和Tyk2，对JAK1的作用较弱。

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  • LDC000067 EY0716

    LDC000067是新型高选择性CDK9抑制剂，IC50值为32.7nM，对CDK2,1,4,6,7的选择性分别为55,125,210,>227,>227倍。

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  • Olanzapine EY0717

    Olanzapine是5-HT2和D2受体高亲和性拮抗剂。

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  • Hydrocortisone EY0727

    Hydrocortisone (氢化可的松) 为主要的糖皮质素，由肾上腺皮质分泌。

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