Pifithrin-α (PFTα)是一种p53抑制剂,抑制p53依赖性的p53应答基因转录。
MoreSB590885是B-Raf的抑制剂,Ki为0.16 nM,对其它人类激酶无活性。
MoreRucaparib phosphate是PARP抑制剂,对PARP1的Ki为1.4 nM,对PARP其余亚型也有亲和性。
MoreGSK J4 hydrochloride is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM and inactive against a panel of demethylases of the JMJ family.
MoreAEBSF是水溶性的,不可逆的丝氨酸蛋白酶抑制剂,抑制蛋白酶如胰凝乳蛋白酶,激肽释放酶,血纤维蛋白溶酶,凝血酶,胰蛋白酶。
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