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Other Singal pathway


  • GSK J4 HCl EY0977

    GSK J4 hydrochloride is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM and inactive against a panel of demethylases of the JMJ family.

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  • AEBSF HCl EY0983

    AEBSF是水溶性的，不可逆的丝氨酸蛋白酶抑制剂,抑制蛋白酶如胰凝乳蛋白酶，激肽释放酶，血纤维蛋白溶酶，凝血酶，胰蛋白酶。

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  • Tofacitinib Citrate EY0953

    Tofacitinib (CP-690550) Citrate是一种新型JAK3抑制剂，IC50为1 nM，作用于JAK2和JAK1选择性比其低20到100倍。

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  • GW4064 EY0957

    GW4064是一种farnesoid X receptor(FXR)（法尼酯X受体）激动剂，EC50为65 nM。

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  • Nutlin-3a EY0963

    Nutlin-3a是Nutlin-3的活性对映体，抑制p53/MDM2相互作用，IC50为90 nM。

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