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Other Singal pathway


  • OG-L002 EY1384

    OG-L002是一种有效的，特异性的LSD1抑制剂，IC50为20 nM，比作用于MAO-B和MAO-A选择性分别高36和69倍。

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  • Celastrol EY1392

    Celastrol is a potent antioxidant and anti-inflammatory agent and a novel HSP90 inhibitor.

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  • Fedratinib EY1393

    TG-101348 (SAR302503)是JAK2选择性抑制剂，IC50为3 nM，作用于JAK2比作用于JAK1和JAK3选择性高35和334倍，同时还能抑制BRD4，IC50为340 nM。

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  • AICAR EY1360

    AICAR 是AMPK活化剂，可作用于急性淋巴细胞白血病。

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  • GKT137831 EY1361

    GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140(plusmn)40 nM and 110(plusmn)30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis.

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